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JWH-018 is a sort of analgesic chemical within the naphthoylindole loved ones that features as a full agonist at each the CB1 and CB2 cannabinoid receptors. It absolutely was 1st synthesized by Dr. John W. Huffman and has long been found in herbal smoking blends like Spice. The analgesic effects of cannabinoid ligands, which might be mediated by CB